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Information for Patients & Caregivers

A knee replacement concept as unique as you are

You are unique and so is your individual anatomy. That’s why Biomet now offers Signature Personalised Patient Care, which utilises MRI (magnetic resonance imaging) technology to create personalised positioning guides for total knee replacement.

It is important to note that your surgeon will still be using the implants he or she feels are best for you.

What is the Signature System

The Signature system utilises custom femoral and tibial positioning guides developed from your MRI. The MRI is used to create a three-dimensional joint reconstruction, which enables the surgeon to preoperatively plan your knee replacement. In the past, surgeon planning has typically been based off of two-dimensional X-rays.

When used in conjunction with the Signature system, the Vanguard Complete Knee System from Biomet allows orthopedic surgeons to provide more of a custom fit specifically for you, regardless of race, size, or gender. The Vanguard knee offers twice the femoral size options of other knee systems, which allows for 90 different size combinations.

Before Your Knee Replacement Surgery

Your preoperative experience will be like that of most total knee patients except that an MRI of your affected leg will be required. The advantage of using MRI is that, unlike an X-ray, it creates a detailed three-dimensional image of your unique anatomy that enables the surgeon to preoperatively plan your knee replacement. Typically, surgeons use X-rays to size components before surgery.

During the knee replacement procedure an assortment of instruments are used to verify component sizing and establish proper positioning and alignment. With the MRI and Signature personalised positioning guides, surgeons have access to a greater level of detail and precision for implant position and alignment before the procedure. This allows for personalised implant positioning and may help enhance surgical efficiency.

You can expect the MRI scan to take approximately 20 minutes. The scan will only be performed on your hip, knee and ankle, so your head will remain outside of the machine. The MRI is used for preoperative planning by your surgeon and for the design and manufacture of the Signature personalised positioning guides that will be used during your knee replacement.

During Your Knee Replacement Surgery

The surgical procedure using the Signature personalised positioning guides is similar to traditional total knee replacement with a few exceptions. During traditional total knee surgery, multiple instruments are used to position the guides for removing damaged bone and cartilage. Traditional total knee replacement sometimes uses instruments placed inside the femur (thighbone) and/or tibia (shinbone) to assist with implant alignment and positioning.

Signature personalised positioning guides are placed directly onto your femur and tibia, and therefore do not require instrumentation of the bone canal, allowing for a potentially less invasive procedure. The Signature personalised positioning guides enable the surgeon to position a reduced number of instruments during surgery to carry out the preoperative plan.

If you have questions regarding Signature Personalised Patient Care, please speak with an orthopedic surgeon. Only an orthopedic surgeon can determine what treatment is appropriate. Individual results of total joint replacement may vary. The life of any implant will depend on your weight, age, activity level, and other factors.



Biomet UK, does not practice medicine and does not recommend any particular surgical technique for use on a specific patient. The surgeon who performs any implant procedure is responsible for determining and utilising the appropriate techniques for implanting prosthesis in each individual patient. Biomet UK. is not responsible for selection of the appropriate surgical technique, nor does it advocate a particular technique
to be utilised on an individual patient.

Please note that Biomet’s Signature Personalised Patient Care System is marketed in Europe, Australia, Israel, Korea, New Zealand, and South Africa.